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2h]8-aea  (Cayman Chemical)


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    Structured Review

    Cayman Chemical 2h]8-aea
    2h]8 Aea, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aea/2h+8+aea/pm40596256-142-0-9
    Average 90 stars, based on 1 article reviews
    2h]8-aea - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Phospho-proteomics:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Incubation:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Western Blot:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Expressing:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Concentration Assay:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Control:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Two Tailed Test:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Liquid Chromatography with Mass Spectroscopy:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.

    Clinical Proteomics:

    Article Title: PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis.
    Article Snippet: N-Acylethanolamines (NAEs) are a class of lipid mediators that exhibit anti-inflammatory and appetitesuppressive activities.. Among them, palmitoylethanolamide (PEA) and arachidonoylethanolamide (AEA) bind to peroxisomal proliferator-activated receptor (PPAR) α and cannabinoid receptor CB1, respectively.. N-Acylphosphatidylethanolamine (NAPE) as a precursor of NAEs is biosynthesized from membrane phospholipids by Nacyltransferases, which consist of group IVE cytosolic phospholipase A2ε (cPLA2ε) and PLAAT (phospholipase A and acyltransferase) family enzymes.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d4 in ethanol and 2-AG-d5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Social stress-induced depressive-like symptoms and changes in gut microbial and lipidomic profiles are prevented by pharmacological inhibition of FAAH activity in male rats.
    Article Snippet: The analytical standards of AEA, OEA, and PEA, and their deuterated analogs AEA-d4, OEA-d4 and PEAd4 were purchased from Cayman Chemical (Ann Arbor, MI, USA) as stock solutions in ethanol.

    Article Title: Study on the mechanism of Panax notoginseng-Salvia miltiorrhiza herb pair on invigorating blood circulation and eliminating blood stasis by blocking the conversion of arachidonic acid to prostaglandin.
    Article Snippet: We combined untargeted and targeted metabolomics to explore the mechanism of blood circulation and blood stasis activation in the traditional Chinese herb pair Panax notoginseng–Salvia miltiorrhiza (PS).. In this study, the right hind limb of SD rats was struck by a 1 kg weight, causing traumatic blood stasis (TBS) model, then the rats were gavaged with PS (at ratios of 1:0, 0:1, 3:1, 1:1, and 1:3) for 5 consecutive days.. At the end of treatment, blood samples were collected for blood rheology and metabolomics analysis, and muscle tissues of injured limbs were used for HE staining and q-PCR analysis.

    Article Title: Investigating Runner’s High: Changes in Mood and Endocannabinoid Concentrations after a 60 min Outdoor Run Considering Sex, Running Frequency, and Age
    Article Snippet: AEA (95 μg/mL in ethanol), 2-AG (9500 μg/mL in acetonitrile) and their respective internal standards (AEA-d 4 in ethanol and 2-AG-d 5 in acetonitrile, both 1 mg/mL) were supplied by Cayman Chemical (Ann Arbor, MI, USA).

    Article Title: Positive allosteric modulation of the cannabinoid CB 1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
    Article Snippet: AEA and 2-AG were purchased from Cayman Chemical Company (Ann Arbour, MI, USA) and constituted and stored at 31.6 mM in EtOH.



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    2h]8-aea  (Cayman Chemical)
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    Cayman Chemical 2h]8-aea
    2h]8 Aea, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aea/2h+8+aea/pm40596256-142-0-9
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    2h]8-aea - by Bioz Stars, 2026-10
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    unlabeled aea  (Tocris)
    93
    Tocris unlabeled aea
    Unlabeled Aea, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aea/Anandamide/pm40596256-175-44-46
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    d8-arachidonoylethanolamide (d8-aea)  (Cayman Chemical)
    90
    Cayman Chemical d8-arachidonoylethanolamide (d8-aea)
    D8 Arachidonoylethanolamide (D8 Aea), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aea/aea+d8/pm40600844-89-7-40
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    deuterated standards [ 2 h] 8 -aea  (Cayman Chemical)
    90
    Cayman Chemical deuterated standards [ 2 h] 8 -aea
    Effect of PGA on the endogenous levels of <t>AEA,</t> 2-AG <t>and</t> <t>PEA</t> in HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. *** P < 0.001 and **** P < 0.0001: Vehicle vs. PGA. D-F Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 6 h. Student’s t test was used for analysis. * P < 0.05 and ** P < 0.01: Vehicle vs. PGA.
    Deuterated Standards [ 2 H] 8 Aea, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aea/deuterated+standards+++2+h++8++aea/pmc12218337-139-5-19
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    aea hydrolysis  (Tocris)
    93
    Tocris aea hydrolysis
    Effect of PGA on the endogenous levels of <t>AEA,</t> 2-AG <t>and</t> <t>PEA</t> in HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. *** P < 0.001 and **** P < 0.0001: Vehicle vs. PGA. D-F Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 6 h. Student’s t test was used for analysis. * P < 0.05 and ** P < 0.01: Vehicle vs. PGA.
    Aea Hydrolysis, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aea/Anandamide/pmc12218337-172-0-43
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    Image Search Results


    Effect of PGA on the endogenous levels of AEA, 2-AG and PEA in HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. *** P < 0.001 and **** P < 0.0001: Vehicle vs. PGA. D-F Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 6 h. Student’s t test was used for analysis. * P < 0.05 and ** P < 0.01: Vehicle vs. PGA.

    Journal: Scientific Reports

    Article Title: Deciphering the interaction between N -palmitoyl-D-glucosamine and the endocannabinoidome

    doi: 10.1038/s41598-025-07103-5

    Figure Lengend Snippet: Effect of PGA on the endogenous levels of AEA, 2-AG and PEA in HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. *** P < 0.001 and **** P < 0.0001: Vehicle vs. PGA. D-F Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with PGA (10 µM), or Vehicle for 6 h. Student’s t test was used for analysis. * P < 0.05 and ** P < 0.01: Vehicle vs. PGA.

    Article Snippet: Deuterated standards—[ 2 H] 8 -AEA, [ 2 H] 5 −2-AG and [ 2 H] 4 -PEA—were purchased from Cayman Chemical (Cabru, Arcore, Italy).

    Techniques:

    Effect of PGA on the endogenous levels of AEA, 2-AG and PEA in SH-SY5Y and RBL-2H3 cells. A-C Concentrations of AEA, 2-AG and PEA in SH-SY5Y cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. * P < 0.05 and ** P < 0.01: Vehicle vs. PGA. D-F Concentrations of AEA, 2-AG and PEA in RBL-2H3 cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. * P < 0.05: Vehicle vs. PGA.

    Journal: Scientific Reports

    Article Title: Deciphering the interaction between N -palmitoyl-D-glucosamine and the endocannabinoidome

    doi: 10.1038/s41598-025-07103-5

    Figure Lengend Snippet: Effect of PGA on the endogenous levels of AEA, 2-AG and PEA in SH-SY5Y and RBL-2H3 cells. A-C Concentrations of AEA, 2-AG and PEA in SH-SY5Y cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. * P < 0.05 and ** P < 0.01: Vehicle vs. PGA. D-F Concentrations of AEA, 2-AG and PEA in RBL-2H3 cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. * P < 0.05: Vehicle vs. PGA.

    Article Snippet: Deuterated standards—[ 2 H] 8 -AEA, [ 2 H] 5 −2-AG and [ 2 H] 4 -PEA—were purchased from Cayman Chemical (Cabru, Arcore, Italy).

    Techniques:

    Effect of Glucosamine on the endogenous levels of AEA, 2-AG and PEA in HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with Glucosamine (10 µM), or Vehicle for 40 min. D-F Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with Glucosamine (10 µM), or Vehicle for 6 h. Student’s t test was used for analysis.

    Journal: Scientific Reports

    Article Title: Deciphering the interaction between N -palmitoyl-D-glucosamine and the endocannabinoidome

    doi: 10.1038/s41598-025-07103-5

    Figure Lengend Snippet: Effect of Glucosamine on the endogenous levels of AEA, 2-AG and PEA in HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with Glucosamine (10 µM), or Vehicle for 40 min. D-F Concentrations of AEA, 2-AG and PEA in HaCaT cells treated with Glucosamine (10 µM), or Vehicle for 6 h. Student’s t test was used for analysis.

    Article Snippet: Deuterated standards—[ 2 H] 8 -AEA, [ 2 H] 5 −2-AG and [ 2 H] 4 -PEA—were purchased from Cayman Chemical (Cabru, Arcore, Italy).

    Techniques:

    Effect of MAFP (10 µM) on the endogenous levels of AEA, 2-AG and PEA in PGA-treated HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells co-treated with PGA (10 µM) and MAFP (10 µM), or Vehicle for 40 min. One-way ANOVA followed by Tukey’s multiple comparison test was used for analysis. ** P < 0.01 and **** P < 0.0001: Vehicle vs. PGA; ** P < 0.01 and **** P < 0.0001: Vehicle mix vs. PGA + MAFP.

    Journal: Scientific Reports

    Article Title: Deciphering the interaction between N -palmitoyl-D-glucosamine and the endocannabinoidome

    doi: 10.1038/s41598-025-07103-5

    Figure Lengend Snippet: Effect of MAFP (10 µM) on the endogenous levels of AEA, 2-AG and PEA in PGA-treated HaCaT cells. A-C Concentrations of AEA, 2-AG and PEA in HaCaT cells co-treated with PGA (10 µM) and MAFP (10 µM), or Vehicle for 40 min. One-way ANOVA followed by Tukey’s multiple comparison test was used for analysis. ** P < 0.01 and **** P < 0.0001: Vehicle vs. PGA; ** P < 0.01 and **** P < 0.0001: Vehicle mix vs. PGA + MAFP.

    Article Snippet: Deuterated standards—[ 2 H] 8 -AEA, [ 2 H] 5 −2-AG and [ 2 H] 4 -PEA—were purchased from Cayman Chemical (Cabru, Arcore, Italy).

    Techniques: Comparison

    Effect of PGA on the endogenous levels of AEA, 2-AG and PEA in ABHD4-silenced HaCaT cells. A Bar chart with individual points showing the mRNA expression levels of ABHD4 in control HaCaT cells (scramble) and siRNA ABHD4 transfected HaCaT cells. Student’s t test was used for analysis. **** P < 0.0001: scramble vs. siRNA. B-D Concentrations of AEA, 2-AG and PEA in ABHD4-silenced HaCaT cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. * P < 0.05 and *** P < 0.001: Vehicle vs. PGA.

    Journal: Scientific Reports

    Article Title: Deciphering the interaction between N -palmitoyl-D-glucosamine and the endocannabinoidome

    doi: 10.1038/s41598-025-07103-5

    Figure Lengend Snippet: Effect of PGA on the endogenous levels of AEA, 2-AG and PEA in ABHD4-silenced HaCaT cells. A Bar chart with individual points showing the mRNA expression levels of ABHD4 in control HaCaT cells (scramble) and siRNA ABHD4 transfected HaCaT cells. Student’s t test was used for analysis. **** P < 0.0001: scramble vs. siRNA. B-D Concentrations of AEA, 2-AG and PEA in ABHD4-silenced HaCaT cells treated with PGA (10 µM), or Vehicle for 40 min. Student’s t test was used for analysis. * P < 0.05 and *** P < 0.001: Vehicle vs. PGA.

    Article Snippet: Deuterated standards—[ 2 H] 8 -AEA, [ 2 H] 5 −2-AG and [ 2 H] 4 -PEA—were purchased from Cayman Chemical (Cabru, Arcore, Italy).

    Techniques: Expressing, Control, Transfection